Curriculum

ACT 830 – SEMINARS IN CLINICAL AND TOXICOLOGICAL ANALYSIS

Student’s presentation of seminars related to research into clinical and toxicological analysis.

ACT 831 – Advanced methods applied to laboratory analysis

The lectures should prioritize the state-of-the-art of the main and most modern laboratory methods (methodological basis, application, interpretation and other related or relevant issues), used or not in the PPGACT research lines. Seminars and discussion groups will complement the teaching strategy.

ACT 810 – Immunotoxicology

To assess the interaction of xenobiotics with the immune system, investigate potential immunological effects, through functional assays such as lymphoproliferative response, antibody production, protein and globulin levels, and histological evaluation of the spleen. Provide scientific subsidies for the safe use of the analyzed extracts.

ACT 814 – Pathophysiology of the Red and White Series

This course aims to study the origin, maturation, physiology, and pathology of the red and white series, with a focus on laboratory diagnosis. Clinical case study.

ACT 817 – Genetics of Cardiovascular Diseases

Conceptual aspects related to the main genetic risk factors and how they participate in the pathophysiology of atherosclerotic cardiovascular disease.

ACT 819 – Laboratory Procedures for Cultivation of Pathogenic Protozoa

Theoretical-practical study of the in vitro isolation and in vitro culture of protozoan luminal and tissue parasites, covering the maintenance of the samples and comparative and critical analysis of the techniques and their applications.

ACT 821 – Use of Biomarkers in the Evaluation of Occupational and Environmental Exposure to Chemical Substances

Provide basic knowledge in occupational and environmental toxicology, foundations of biological monitoring of the functioning of chemical environments and their biomarkers, within a global context of worker health and environmental health, in addition to toxicological and laboratory exposure to some toxic agents.

ACT 822 – Hemostasis Disorders

The aim of the course is to address the physiological factors of hemostasis, disorders related to vessels, platelets, coagulation factors, natural anticoagulants and fibrinolysis, focusing on laboratory methods for the diagnosis of hypo and hypercoagulability.

ACT 823 – Multidisciplinary Themes of Interest in Applied Research

This course aims to address methods of data analysis applied in clinical research and updated topics of interest primarily in hypercoagulant / thrombotic / atherosclerotic states.

ACT 824 – Advanced Topics in Platelets

This course aims at the study and discussion of new approaches in platelet physiology and pathology, with potential application in the laboratory diagnosis of conditions associated with hypercoagulability / platelet hyperactivation.

ACT 825 – New Trends in Imaging Diagnosis

Radiolabeled red blood cells for the evaluation of the cardiac function, hemangioma investigations, and gastrointestinal tract bleeding. Autologous radiolabeled leukocytes for investigations of fever of unknown origin, of inflammatory and infectious processes, excluding bones and intestine. Differentiation of aseptic inflammation using radiolabeled antibiotics.

ACT 826 – Topics in Virology

Introduction to virology and determination of structure, morphology, classification, organization of the genome and virus multiplication. The main families of viruses of clinical interest. Pathogenesis of viral infections and diagnostic methods used in virology. Control and prophylaxis of viral infections.

ACT 827 – CONCEPTS IN IMMUNOLOGY

Current knowledge of Immunology. Seminars and advanced issues about Immunology followed by critical analysis. Revision of basic notions on the Immune System and updating the advancement of knowledge of the Immune System through reading and discussing revision articles published in the last five years. Emphasis on the study of the kinds of immune response and its general properties and fundaments which rule immune responses. Descriptions of the effector immunity mechanisms of cells and tissues of the immune systems. Emphasis on organizing and relationships between structure and function.

ACT 832 – Principles of Biostatistics

The role of statistics in health sciences research. Descriptive and exploratory data analysis. Introduction to Probability. Probability Distributions: Binomial and Normal. Basic Concepts of Statistical Inference. Hypothesis Testing and Confidence Intervals. Hypothesis test for a population. Comparison of two groups: proportions and averages tests for paired samples and for independent samples. Quantification of the effect: difference of means, relative risk, and odds ratio.

ACT 833 – Scientific Methodology

Study of basic methods of scientific research, elaboration of technical texts, dissertations, and theses, plus critical discussion of articles with reference to the understanding of the writing of articles. SUMMARY OF THE THEMATIC CONTENTS: Study of basic methods of scientific research, including sources of information; Stages of scientific work (pre-textual, textual, and post-textual elements), and standardization of scientific work (quotations, references, and notes).

ACT 836 – Study of Inflammation in Infectious Diseases

Study of the concepts related to the inflammatory response and its mediators and the inflammatory mechanisms involved in the pathophysiology of viral and bacterial infectious diseases.

ACT 837 – Topics in Bacteriology

Study of the morphology, physiology, genetics, pathology, isolation, and identification of the main bacteria causing diseases in humans, as well as methodologies for isolation and identification.

ACT 839 – Nanotechnology and Radiotracers

Basic knowledge of radiation. Preparation, characterization and application of radiolabeled nanostructures for identifying physiopathologic process in experimental models.

ACT 840 – Interrelation of Biochemical, Hematological, and Immunologic Markers in Transplanted Patients

Diabetes mellitus and pancreas transplantation; Kidney diseases and kidney transplantation; Cardiovascular diseases and heart transplantation; Liver diseases and liver transplantation; Interrelation of biochemical, hematological, and immunological markers in transplanted patients.

ACT 841 – Topics in Clinical and Toxicological Analysis I

Subjects of interest to students, not included in other disciplines, raised in the evaluation of professional practice, in the form of seminars, also involving as research activities.

ACT 842 – Topics in Clinical and Toxicological Analysis II

Subjects of interest to students, not included in other disciplines, raised by the evaluation of professional practice, presented in the form of seminars, also involving research activities.

ACT 843 – Topics in Clinical and Toxicological Analysis III

Subjects of interest to students, not included in other disciplines, raised by the evaluation of professional practice, presented in the form of seminars, also involving research activities.

ACT 844 – Topics in Clinical and Toxicological Analysis IV

Subjects of interest to students, not included in other disciplines, raised by the evaluation of professional practice, presented in the form of seminars, and also involving research activities.

ACT 845 – Human Molecular Genetics

The aim of this course is to discuss the main characteristics and structure of the human genome, the types and model of inheritance, the genes in the genealogies, the relationship between genotype and phenotype, and techniques for human genome study.

ACT 846 – Preclinical Toxicology: Regulatory Aspects and Alternative Methods to Animal Experimentation

Preclinical evaluations used in the study of therapeutic products according to the current legislation of the main world regulatory bodies.

ACT 847 – Advanced Methods in Clinical and Toxicological Analysis

Provide basic and advanced knowledge in chromatographic techniques (gas chromatography and high performance liquid chromatography) and spectrometric techniques (atomic absorption and ICP-MS) and their applications in Clinical and Toxicological Analysis. To provide knowledge and application of the validation of analytical methods using chromatography and spectrometric techniques.

ACT 848 – Entrepreneurship

Entrepreneurial Profile; Concept of Information Technology Systems; Creativity; Visionary Process; Study of Opportunities; Network of Relationships; Business plan. Importance of the creation of small and mid-sized enterprises. Policies and programs to support small and mid-sized enterprises. Skills, profile, and behavior of the leader of small and mid-sized enterprises; Typical problems of small and mid-sized enterprises; Training and development of entrepreneurs; Profile of the successful entrepreneur.

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