Laboratory diagnosis and therapy: hemostasis, inflammation, infection and neoplasia
Studies on hemostatic, cellular, biochemical, and molecular aspects through new laboratory methods and research of new biomarkers with potential application in the prevention, prognosis, diagnosis, and monitoring of treatment of diseases that can present with hypercoagulability, as well as inflammatory, infectious, and neoplastic diseases.
Investigations related to the diagnosis and therapy of inflammatory, infectious, neoplastic, and toxicological processes
Aims to foster in-depth studies on cell signaling in inflammation; interactions between the plasminogen system and inflammation, and study of inflammation in experimental models of infectious diseases; use of radiolabeled long-circulating, pH-sensitive Liposomes for identifying prostate tumor and other diseases in an experimental model; development of recombinant vaccines against leishmaniosis comprising the identification and characterization of recombinant antigens capable of inducing protection against Leishmania infection; treatment and immunotherapy of Leishmaniosis; new alternatives for diagnosis of Visceral Leishmaniosis; epidemiology and molecular diagnostic of major pathogens in infectious diseases, STD agents such as HPV, Chlamydia, Neisseria gonorrhoeae, Mycoplasma and Ureaplasma, and waterborne protozoa such as Cryptosporidium, Giardia and Acanthamoeba.
Biomarkers in Clinical and Toxicological Analysis
Aims to conduct studies in order to identify new biomarkers for use in the clinical practice and correlate genetics and phenotype in patients with several diseases, as well as safety assessment studies of new drugs through preclinical toxicity tests (in vivo and in vitro).